Efficacy and Tolerability of Fluticasone Propionate/Salmeterol MDI Compared With Concurrent Fluticasone Propionate and Salmeterol MDI in Adult Patients with Persistent Asthma: A Randomized, Double-Blind 12-Week Study
نویسنده
چکیده
Background: The use of a single inhaler to administer a dry powder formulation of fluticasone (FP) and salmeterol (SM) is at least as effective as concurrent administration of the mono-components from individual dry powder inhalers. Whether the same applies to the pressurised metered dose inhaled (pMDI) formulation of these products which, unlike the dry powder formulations are not breath-actuated, has not been established.
منابع مشابه
Safety and Efficacy of Fluticasone Propionate/Salmeterol Hydrofluoroalkane 134a Metered-Dose-Inhaler Compared with Fluticasone Propionate/Salmeterol Diskus in Patients with Chronic Obstructive Pulmonary Disease
PURPOSE To provide information on the efficacy and safety of Fluticasone Propionate/Salmeterol Hydrofluoroalkane 134a Metered-Dose-Inhaler 230/42mcg (FSC MDI) and its comparable dose of Fluticasone Propionate/Salmeterol DISKUS 250/50mcg (FSC DISKUS) in patients with COPD. METHODS This multicenter, randomized, double-blind, 12 week study was designed to evaluate FSC MDI treatment responses as ...
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BACKGROUND The inhaled corticosteroid (ICS) fluticasone propionate (fluticasone) and the long-acting β2-agonist (LABA) formoterol fumarate (formoterol) are being made available as a combination product (fluticasone/formoterol, flutiform ®) in a single aerosol inhaler. This 12-week, open-label, randomized, active-controlled, parallel-group, multicentre, phase 3 study compared the efficacy and sa...
متن کاملCost-effectiveness comparison of salmeterol/fluticasone propionate versus montelukast in the treatment of adults with persistent asthma.
OBJECTIVE To compare the relative cost effectiveness of salmeterol (50 microg)/ fluticasone propionate (100 microg) with that of oral montelukast (10mg) as initial maintenance therapy in patients with persistent asthma uncontrolled on short-acting beta2-agonist therapy alone. STUDY DESIGN A cost-effectiveness analysis was performed based on effectiveness and resource utilisation data that was...
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تاریخ انتشار 2017